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Zestril Description Zestril belongs to a group of drugs called the ACE (angiotensin converting enzyme) inhibitors. Lisinopril is the active ingredient in Zestril and is used for treating heart attacks, congestive heart failure and hypertension and also for preventing retinal and renal complications and complexities of diabetes. The ingredient is hydrophilic, penetrates liver but is not metabolized by the organ. Developed by Merck & Co, Lisinopril is globally marketed as Tensopril or Prinivil and as Zestril by AstraZeneca. Zestril is available in tablet form and comes in the following dosage strengths: 2.5 mg, 5, 10, 20, 30 and 40 mg tablets. These tablets should be stored at room temperature and away from moisture and light. Conditions treated by Zestril Lisinopril or Zestril is primarily prescribed for treating heart failure and elevated blood pressure levels and also for improving survival post a myocardial infarction or heart attack. Angiotensin is a chemical made continuously by the body that narrows blood vessels for maintaining blood pressure levels. When Zestril blocks this enzyme, angiotensin will not be able to convert into its active form. Because of this, dilation of blood vessels occur and blood pressure levels fall. High blood pressure is treated in children and adults over 6 years of age. Reducing blood pressure prevents kidney problems, heart attacks and strokes. The drug is also prescribed for use after an acute heart attack to make sure chances of survival improve. When used with other drugs such as digoxin and diuretics, congestive heart failure can be treated.

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